Aparthotel vacation rentals in Panama

Find and book unique aparthotel rentals on Airbnb

Top-rated aparthotels in Panama

Guests agree: these aparthotel rentals are highly rated for location, cleanliness, and more.

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Hotel room in Panamá

Standard room with terrace and panoramic city view

Enjoy a comfortable stay in this standard room for 2 people in an aparthotel located in the heart of the Old Town of Panama City. With 20 m² of spacious and bright space, it is ideal for couples or travellers looking for an excellent location and all the amenities. Surrounded by restaurants, cafeterias and the main tourist spots such as Tomás Herrera Park, Independence Square and the Interoceanic Canal Museum, this accommodation offers easy access to the metro, buses and airports.

A living area featuring two distinct chairs in red and blue upholstery. A sleek television is mounted on the wall, while a round side table sits in front. Natural light filters through sheer curtains, enhancing the contemporary design.

Hotel room in Panamá

Incredible Suite in Panama

Discover the comfort of this elegant 40 m² Deluxe Suite, perfect for 2 people, located in the heart of the Old Town of Panama City. Ideal for those seeking spaciousness, style, and an excellent location. Enjoy a lively environment, surrounded by restaurants, cafés and the main tourist attractions such as the Canal Museum, Independence Square and the Presidential Palace. Includes: wifi, air conditioning, Tv, hairdryer, spa, private balcony and kitchen with coffee maker.

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Hotel room in Panamá

The Urban Loft #203 | La Résidence Panamá

Contemporary comfort for the modern traveler. This 69-71 m² suite includes 2 bedrooms (two king beds - bedroom open in pb+ one sofabed), 2 bathrooms, full kitchen, washer/dryer, coffee machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With a blend of modern design, central location, and thoughtful amenities, we create a space built for your comfort and productivity.

A charming outdoor seating area is surrounded by lush greenery and vibrant potted plants. Comfortable wicker furniture is arranged under a canopy of clear roofing, providing shade. Colorful cushions add a welcoming touch to the space, while terracotta tiles create a warm flooring throughout.

Hotel room in Alto Boquete

4.57 out of 5 average rating, 23 reviews

Charming house and total relaxation. Cabaña #2

Escape to Boquete: Experience the romance at Villa San Miguel. If you are looking for an intimate and cozy corner to share special moments, Villa San Miguel is the place to be. Surrounded by nature and with a warm atmosphere, this villa allows you to disconnect from the noise and connect with the important. Perfect for honeymooners, anniversaries or just to get away together for a few days.

A welcoming exterior view of Serenade Lodging Rooms features a prominent sign amidst lush greenery and a well-maintained entrance. Stone accents enhance the modern façade, and a pathway leads to the building, providing easy access for guests.

Hotel room in Panamá

4.79 out of 5 average rating, 28 reviews

Serenade Lodging Rooms

Si necesitas un lugar donde te quieras sentir en casa fuera de tu casa, Serenade Lodging Rooms te lo ofrece.Habitaciones súper cómodas,con su cocineta incluida ... todo con los mejores estándares.. Desayuno completo incluido.. delicioso y variado.. y una excelente atención pues en Serenade Lodging Rooms usted es nuestra prioridad.

A small balcony features a round, white, metal table and two matching chairs. A newspaper is spread open on the table next to a cup of coffee and a colorful pastry. The balcony overlooks a charming street, with bright light filtering through the lush plants.

Hotel room in Panamá

Deluxe Suite in the Heart of Panama City

Enjoy an exclusive stay in our 30 m² Deluxe Suite, a modern, comfortable accommodation filled with natural light, ideal for two people. Located in the heart of Panama City's historic district, this apart-hotel places you steps away from the main tourist, cultural, and gastronomic attractions.

A bright living area features a round glass dining table with four black chairs. A red couch is positioned against the wall, while a kitchenette is equipped with a stove, refrigerator, and various appliances. A wall-mounted television is visible, along with light-colored walls and tiled flooring.

Hotel room in Panama City

4.82 out of 5 average rating, 11 reviews

COMFORTABLE APARTMENT IN THE CRAB

Fully furnished private apartments for 2 people, 30m2 with 1 room, kitchen, private bathroom, dining room. The balcony area is communal. Includes air conditioning and hot water. Located in city center, close to restaurants, pharmacies, mini-markets, karaoke karaoke, among other amenities.

A tranquil pool area is featured, accented by decorative planters and a round float resting on the water's surface. A light-colored building can be seen in the background, complemented by lush green trees. A vehicle is parked nearby, adding to the convenience of the setting.

Hotel room in Llano de Mariato

Captiva House

Enjoy with all the family and friends with our spacious rooms in Mariato, we have a pool, barbecue area and our location is close to shops in the town. 5 minutes from Playa Reina and also close to Playa thorio, playa hidida and others.