Some info has been automatically translated. Show original language

Guesthouse vacation rentals in Panama

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouses in Panama

Guests agree: these guesthouses are highly rated for location, cleanliness, and more.

Guest favourite
Guesthouse in Pedasi
A Remote Paradise in nature - Ocean View
'Tres-Palmas' sea and nature at its best! A remote hideaway on the Pacific Coast of Panama, but yet close enough to nearby towns and entertainment, Tres Palmas is the perfect place for an invigorating holiday. It is more than just a place to stay, we offer our guests personalized attention through fully equipped facilities and services for your comfort and well being. We enjoy getting to know our guests, sharing life stories and greeting you with an authentic smile for an unforgettable stay.
Sep. 22 – 29
$195 CAD per night
5.0 out of 5 average rating, 19 reviews
Guest favourite
Guesthouse in Torio
Torio guesthouse with panoramic view
Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.
Oct. 16 – 23
$110 CAD per night
4.9 out of 5 average rating, 105 reviews
Guest favourite
Guesthouse in Jaramillo
Wonderful view Boquete private mountain estate
This is in 1 of 4 beautiful, Top Rated units at our estate, with a price range for every budget. Experience the peace and tranquility, amazing view and 2.5 acres of beautiful tropical gardens bounded by cloud forest at our stunning, private mountain estate ‘Casa Vista Volcan’. Surrounded by nature you will fall asleep to the sounds of the cloudforest and wake to birdsong! Facing West to Volcano Baru, we are just 10 minutes by car/7Km from down town Boquete, adjacent to the National Park.
May 25 – Jun. 1
$84 CAD per night
4.98 out of 5 average rating, 266 reviews

Popular amenities for Panama guesthouses

Family-friendly guesthouses

Guest favourite
Guesthouse in Panamá
Private cottage in the heart of the city
Oct. 30 – Nov. 6
$124 CAD per night
4.74 out of 5 average rating, 226 reviews
Guest favourite
Guesthouse in Mariato
Beachfront/Private Full floor Studio in Guesthouse
Dec. 26 – Jan. 2
$151 CAD per night
4.95 out of 5 average rating, 60 reviews
Guest favourite
Guesthouse in Nueva Gorgona
Beautiful Casita-Paradise in Panama, Nueva Gorgona
Sep. 5 – 12
$112 CAD per night
4.99 out of 5 average rating, 67 reviews
Guesthouse in Bocas del Toro Province
Las Palmas Casita at Bluff Beach Retreat
Aug. 17 – 24
$404 CAD per night
5.0 out of 5 average rating, 4 reviews
Guesthouse in Alto Boquete
Accommodation. Sinsonte )
Jul. 30 – Aug. 6
$122 CAD per night
4.82 out of 5 average rating, 65 reviews
Guest favourite
Guesthouse in Jaramillo Arriba
Cottage Sait
Jan. 6 – 13
$362 CAD per night
4.92 out of 5 average rating, 37 reviews
Guesthouse in Boquete
Vista a Baru
Nov. 9 – 16
$369 CAD per night
5.0 out of 5 average rating, 9 reviews
Guesthouse in Chicá
Villa Altos de Campana, guess house for 6
Apr. 24 – May 1
$214 CAD per night
New place to stay
Guesthouse in Panamá
Mochila & Art Family House
Oct. 22 – 29
$62 CAD per night
New place to stay
Superhost
Guesthouse in Panamá
Private cabin and CasaMomote River, Loma Limón.
May 27 – Jun. 3
$68 CAD per night
4.92 out of 5 average rating, 37 reviews
Guest favourite
Guesthouse in PA
La Rosa de Los Vientos, Pedasi, double room
Jul. 11 – 18
$69 CAD per night
4.8 out of 5 average rating, 15 reviews
Guesthouse in Saboga
SUMMER FANTASY ( located on Contadora Island)
Sep. 6 – 13
$110 CAD per night
New place to stay

Guesthouses with a patio

Superhost
Guesthouse in Panamá Oeste
Mountain house with pool in Panama
May 17 – 24
$234 CAD per night
4.73 out of 5 average rating, 83 reviews
Guest favourite
Guesthouse in Anton Valley
Cabin The India
Jul. 20 – 27
$94 CAD per night
4.82 out of 5 average rating, 17 reviews
Guest favourite
Guesthouse in Anton Valley
Private 1 BR cottage near India Dormida hiking
Jun. 16 – 23
$76 CAD per night
4.9 out of 5 average rating, 39 reviews
Guest favourite
Guesthouse in Bajo Boquete
Downtown Rustic Studio
May 15 – 22
$57 CAD per night
5.0 out of 5 average rating, 19 reviews
Guest favourite
Guesthouse in Bajo Boquete
Mini suite in low boquete
Jul. 29 – Aug. 5
$76 CAD per night
4.7 out of 5 average rating, 10 reviews
Guest favourite
Guesthouse in Almirante
Entire guesthouse in Almirante, Bocas
May 11 – 18
$48 CAD per night
4.85 out of 5 average rating, 20 reviews
Guest favourite
Guesthouse in Alto Boquete
Bungalow Villa Castillo, Boquete.
Mar. 21 – 28
$65 CAD per night
4.77 out of 5 average rating, 13 reviews
Superhost
Guesthouse in El Valle de Antón
Private Suite/Studio 1-Bedroom in Paradise
Apr. 10 – 17
$116 CAD per night
New place to stay
Superhost
Guesthouse in Rio Sereno
The Farmer’s Shack - Pure Nature
Nov. 9 – 16
$70 CAD per night
5.0 out of 5 average rating, 3 reviews
Guesthouse in Torio
Olé #2 | Close the beach, restaurants, activities
Aug. 23 – 30
$56 CAD per night
4.71 out of 5 average rating, 17 reviews
Guesthouse in Panamá
Independent Attachment
Apr. 6 – 13
$50 CAD per night
5.0 out of 5 average rating, 4 reviews
Guesthouse in Almirante
Gia's Garage & Home for Bocas travelers
Mar. 5 – 12
$42 CAD per night
4.59 out of 5 average rating, 44 reviews

Guesthouse rentals with a washer and dryer

Guest favourite
Guesthouse in El Valle de Antón
Spacious Casita with Bamboo View
Nov. 8 – 15
$120 CAD per night
5.0 out of 5 average rating, 24 reviews
Guest favourite
Guesthouse in Gamboa
Gamboa Toucan Apartment casa # 126
Sep. 11 – 18
$119 CAD per night
4.94 out of 5 average rating, 52 reviews
Superhost
Guesthouse in Bocas del Toro
Tiny Studio w/ pool access
May 24 – 31
$121 CAD per night
4.88 out of 5 average rating, 8 reviews
Guest favourite
Guesthouse in Nueva California
Volcan Cloud Forest Escape for two
Jun. 3 – 10
$96 CAD per night
5.0 out of 5 average rating, 9 reviews
Guest favourite
Guesthouse in Río Hato
Sustainable Guest house with Pool in Rio Hato
Jan. 16 – 23
$121 CAD per night
4.87 out of 5 average rating, 54 reviews
Guest favourite
Guesthouse in Alto Quiel
The Casita at Finca Philadelphia
Sep. 18 – 25
$165 CAD per night
4.98 out of 5 average rating, 50 reviews
Superhost
Guesthouse in Boquete
Cozy Studio Unit with Jawdropping Views!
Apr. 8 – 15
$140 CAD per night
4.6 out of 5 average rating, 5 reviews
Guest favourite
Guesthouse in Boquete District
Duplex 1
Apr. 20 – 27
$153 CAD per night
5.0 out of 5 average rating, 5 reviews
Superhost
Guesthouse in Los Naranjos
Cabaas de Alicia 1
Apr. 3 – 10
$93 CAD per night
4.67 out of 5 average rating, 57 reviews
Guest favourite
Guesthouse in Cambutal
"La Jungla" Cabaña close to the beach
Jul. 31 – Aug. 7
$120 CAD per night
4.83 out of 5 average rating, 6 reviews
Guest favourite
Guesthouse in David
Cozy, quiet and in an excellent location!
Feb. 16 – 23
$46 CAD per night
5.0 out of 5 average rating, 5 reviews
Guest favourite
Guesthouse in Bocas del Toro
The Boat House in Big Bight
May 26 – Jun. 2
$142 CAD per night
5.0 out of 5 average rating, 12 reviews

Destinations to explore