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Vacation home accommodations in Panama

Find and book unique vacation houses on Airbnb

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Top-rated vacation houses in Panama

Guests agree: these vacation houses are highly rated for location, cleanliness, and more.

Superhost
Vacation home in Panamá
Beautiful apartment in the old town with balcony!
Enjoy a stylish and relaxing experience in this very centrally located and quiet accommodation. The apartment is equipped with everything necessary for 4 people. It is situated on the western edge of the beautifully renovated and colorful old town of Panama (Casco Viejo), right next to the church and the main square of Santa Ana. From here you can reach all the highlights of the old town, as well as the lively and multifaceted Av. Central, oder die Küstenpromenade "Cinta Costera". WELCOME to Panama!
Guest favourite
Vacation home in Panama City
Brand New Apartment With Sea View
1 Bedroom, 1 Bathroom, with stunning beach and sea views The resort is surrounded by a beautiful rainforest and natural wildlife. It is a unique tropical oasis with beachfront condominiums adjacent to a neighboring five-star hotel. The Playa Bonita Village resort is located amidst a beautiful rainforest and natural wildlife on an exclusive private beach, adjacent to the Westin Hotel and is just 15 minutes from the city. The resort enjoys beautiful views of the rainforest and the Pacific Ocean.
Superhost
Vacation home in Panamá
Modern Apartment with pool in Casco Viejo
The apartment is located on the first floor, letter K, and has 3 balconies. It is modern and central, in the old town of Panama City, close to restaurants, museums and nightlife. It has everything you need in crockery for 8 people, and in the kitchen, you will find everything to make delicious menus!!!!! It also has laundry, ironing board and iron. We have 2 TVs, and super fast Wi-Fi, 1000 megabytes, so you can connect your favorite app!!!

Popular amenities for Panama vacation houses

Family-friendly vacation houses

Superhost
Vacation home in Juan Gallego
Pebos Reef, 12 guests, Amazing views!!
Guest favourite
Vacation home in El Chirú
Apartment in Buenaventura
Vacation home in La Pintada
La Pintada Inn full hotel for private group
Vacation home in Coronado
Long season rentals. Yearly. Pưparadise
Vacation home in Panamá
Lovely place with exclusive private pool

Vacation home rentals with a patio

Guest favourite
Vacation home in Bocas del Toro
The Pool House, Beach House on Paunch Beach
Guest favourite
Vacation home in Maria Chiquita
Dreamy, Modern Caribbean Home at Playa Escondida
Guest favourite
Vacation home in Bocas del Toro
VISTA DEL MAR @ Casa Rosada Feel the Breeze....
Guest favourite
Vacation home in Playa Los Destiladeros
Curcu House: magical beach house & tropical forest
Guest favourite
Vacation home in Las Escobas del Venado
3 BR Family Surf Villa - Benow in Playa Venao
Superhost
Vacation home in Bajo Boquete
Villa Alejandro - Suite Jardin with balcony
Guest favourite
Vacation home in Maria Chiquita
Charming place in a Tropical Paradise
Guest favourite
Vacation home in Bocas del Toro
Jungle house under the giants at the Bluff Beach
Guest favourite
Vacation home in Coronado
Modern Beach House With Private Beach Access
Superhost
Vacation home in San Carlos
Welcome to our house in Playa Corona
Guest favourite
Vacation home in Anton Valley
Adorable 2 bedroom home near India Dormida hiking
Guest favourite
Vacation home in Chitré
CASA EdditA ° Cozy house in Chitre

Vacation home rentals with a washer and dryer

Superhost
Vacation home in Bocas del Toro Province
Beautiful 2 bedroom open air home jungle home
Guest favourite
Vacation home in Maria Chiquita
**Playa Escondida - Paradise in the caribbean sea
Guest favourite
Vacation home in Maria Chiquita
Entire Aparment Playa Escondida Resort &Marina
Superhost
Vacation home in Arraiján
Apartment In Club De Playa, with Pool and BBQ
Superhost
Vacation home in Maria Chiquita
Playa Escondida apt 200 mt2, 4r 4b waterfront
Vacation home in Panamá
Spectacular and cozy oceanfront apartment
Vacation home in Panama City
Lovely studio apartment in the heart of the city
Guest favourite
Vacation home in Nueva Gorgona
cozy apartament in Gorgona beach
Guest favourite
Vacation home in Maria Chiquita
RENT PLAYA ESCONDIDA, THE BEST KEPT SECRET
Vacation home in Boquete
Studio Apartment in Boquete
Vacation home in Playa Blanca Rio Hato
Comfortable apartment with pool and close to the beach
Guest favourite
Vacation home in Maria Chiquita
Playa Escondida: condo ocean view 3 bedrooms

Destinations to explore