Aparthotel vacation rentals in Panama

Find and book unique aparthotel rentals on Airbnb

Top-rated aparthotels in Panama

Guests agree: these aparthotel rentals are highly rated for location, cleanliness, and more.

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Hotel room in Panamá

Standard room with terrace and panoramic city view

Enjoy a comfortable stay in this standard room for 2 people in an aparthotel located in the heart of the Old Town of Panama City. With 20 m² of spacious and bright space, it is ideal for couples or travellers looking for an excellent location and all the amenities. Surrounded by restaurants, cafeterias and the main tourist spots such as Tomás Herrera Park, Independence Square and the Interoceanic Canal Museum, this accommodation offers easy access to the metro, buses and airports.

Hotel room in Panamá

Increible Suite en Panama

Discover the comfort of this elegant 40 m² Deluxe Suite, perfect for 2 people, located in the heart of the Old Town of Panama City. Ideal for those seeking spaciousness, style, and an excellent location. Enjoy a lively environment, surrounded by restaurants, cafés and the main tourist attractions such as the Canal Museum, Independence Square and the Presidential Palace. Includes: wifi, air conditioning, Tv, hairdryer, spa, private balcony and kitchen with coffee maker.

Hotel room in Panamá

The Urban Loft #203 | La Résidence Panamá

Contemporary comfort for the modern traveler. This 69-71 m² suite includes 2 bedrooms (two king beds - bedroom open in pb+ one sofabed), 2 bathrooms, full kitchen, washer/dryer, coffee machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With a blend of modern design, central location, and thoughtful amenities, we create a space built for your comfort and productivity.

Hotel room in Panamá

Habitacion para 4 huespedes en inmejorable Zona Pa

Spacious and bright Twin Suite of 40 m² with capacity for 4 people, ideal for families or groups of friends. Located in the heart of the Old Town of Panama City, steps away from historic squares, museums, cafes, and restaurants. Modern accommodation, fully equipped with wifi, air conditioning, Tv, hairdryer, spa access and kitchen with coffee maker. Perfect for a comfortable stay in one of the most vibrant areas of the city.

Hotel room in Alto Boquete

4.59 out of 5 average rating, 22 reviews

Casa con encanto y relax total. Cabaña #2

Escápate a Boquete: vive el romance en Villa San Miguel. Si buscas un rincón íntimo y acogedor para compartir momentos especiales, Villa San Miguel es el lugar ideal. Rodeada de naturaleza y con una atmósfera cálida, esta villa te permite desconectar del ruido y conectar con lo importante. Perfecta para lunas de miel, aniversarios o simplemente para escaparse juntos unos días.

Hotel room in Panamá

4.79 out of 5 average rating, 28 reviews

Serenade Lodging Rooms

Si necesitas un lugar donde te quieras sentir en casa fuera de tu casa, Serenade Lodging Rooms te lo ofrece.Habitaciones súper cómodas,con su cocineta incluida ... todo con los mejores estándares.. Desayuno completo incluido.. delicioso y variado.. y una excelente atención pues en Serenade Lodging Rooms usted es nuestra prioridad.

Hotel room in Panama City

4.82 out of 5 average rating, 11 reviews

COMODO APARTAMENTO EN EL CANGREJO

Apartamentos privados completamente amoblados para 2 personas, de 30m2 con 1 habitación, cocina, baño privado, sala-comedor. El área de balcón es comunal. Incluye aire acondicionado y agua caliente. Ubicado en el centro de la ciudad, cerca de restaurantes, farmacias, mini-mercados, karaokes, entre otros servicios.