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Mansion vacation rentals in Panama

Find and book unique mansions on Airbnb

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Popular amenities for Panama mansion rentals

Luxury mansion rentals

Guest favourite
Villa in Las Lajas
4.82 out of 5 average rating, 33 reviews

Beach House Where Emy

TylerRating, 5 stars2 months ago
Great place we want to go back already.
Superhost
Home in La Ermita
4.83 out of 5 average rating, 12 reviews

2 beachfront houses, spectacular private beach.

AlexRating, 5 stars3 months ago
good attention, super equipped house that was what we liked the most, beautiful access of Playa and rio super nearby , the stay was wonderful... keep it up.
Guest favourite
Cottage in Panama City
5 out of 5 average rating, 18 reviews

Hacienda La Perezosa in Cerro Azul

TeddyRating, 5 stars2 weeks ago
Very well maintained and clean. Perfect spot for a relaxing time with ample amenities and service staff. Will definitely repeat!
Superhost
Villa in Rio Hato
4.86 out of 5 average rating, 44 reviews

La Casa de las Uvas, an oasis with ocean views

LoriRating, 5 stars1 month ago
Wonderful stay. The pool, beautiful trees and well thought out outdoor seating was the perfect setting for our large family to vacation. Easy walk to the beach and restaurants. House had everything we needed. Mónica was very responsive to a very small issue we had and it was quickly remedied. Absolutely recommend.
Superhost
Home in Coronado
4.76 out of 5 average rating, 25 reviews

CHARMING HOUSE IN FRONT OF THE SEA WITH POOL-CROWNED

MathieuRating, 5 stars1 month ago
I really loved the Hamacas casa What a beautiful place You can’t go wrong being right on the beach Lots of restaurants near by Super safe to walk around Coronado Marcella was super helpful and answered Us every time we had a question The house was great mind you we didn’t really stay in the house other than going to bed Daniel the grounds keeper was super nice and helpful All and all I wouldn’t definitely rent this place again hopefully in a bear future
Guest favourite
Apartment in Panama City
4.96 out of 5 average rating, 25 reviews

22M Spectacular Penthouse New Design Oceanview

ShawnRating, 5 stars5 months ago
I had an absolutely wonderful stay at Melissa’s place! The space was clean, beautifully maintained, and thoughtfully designed for comfort. Melissa was an exceptional host—very responsive, kind, and accommodating throughout my visit. The location was perfect, with easy access to local attractions and everything I needed nearby. I truly felt at home and appreciated the attention to detail that made my stay so relaxing. I highly recommend this Airbnb and would love to stay here again in the future!
Guest favourite
Villa in Isla Colon
4.89 out of 5 average rating, 9 reviews

Casa Caracola. Luxury villa. 200 mts from beach

GiyoraRating, 5 stars2 months ago
Our stay at casa Caracola was simply exceptional. It is a spacious, luxurious and perfect for two families. From the moment we arrived, we felt so comfortable that we hardly needed to go anywhere. We spent our days enjoying the beautiful garden and swimming pool, where we had the privilege of seeing toucans, monkeys, and a variety of wild birds. Waking up each morning to the sound of birds singing was an incredible experience. The host, Ricardo, was outstanding. He helped us arrange everything, from private chefs who prepared spectacular meals at the house to booking tours and surf and diving lessons. His attention to detail and willingness to assist made our stay even more special. We also want to highlight Nely, who took care of keeping the house spotless throughout our stay. It was a pleasure to have her help in maintaining everything clean and organized. We will definitely be back. A perfect place for an unforgettable getaway! Thanks Gigi
Guest favourite
Home in Bocas del Toro
4.92 out of 5 average rating, 25 reviews

Architectural Waterfront Home - "Casa Comunal"

FrankRating, 5 stars3 months ago
Fantastic place, the sea is your backyard. Monkeys, tracking, squirrels, and surfers on the waves passing by. Great house, minimalist but very nice with various hangouts. Keep in mind that it can be warm in the house and that insects can easily enter....but there is something great about that.

Pet-friendly mansion rentals

Superhost
Place to stay in Portobelo
4.9 out of 5 average rating, 21 reviews

Oceanfront Villa

AdrianaRating, 5 stars2 months ago
This place is perfect to enjoy a relaxing het away, having the beautiful ocean view and tropical breeze right outside of the house it is priceless! The pool and Jacuzzi are well maiy and make a great complement of the whole experience! The host thought about every detail to make the guests very welcome, by providing essentials for personal cleaning products, kitchen extra essentials and outdoors supplies. We really enjoyed the stay.!
Superhost
Cottage in Panamá Oeste
4.83 out of 5 average rating, 12 reviews

Iwanna Green, Country House with Pool

MonicaRating, 5 stars5 months ago
A totally ecological house with activities for the whole family, a pool surrounded by nature and a theme that makes you want to take out your inner child and have a good time with friends and family while you are surrounded by a cool climate in the bell mountain. Easy access, diversity and neon art in each area of the house, multiple cooking utensils and appliances. .
Top guest favourite
Home in Nueva Gorgona
5 out of 5 average rating, 21 reviews

Comfortable beach house with pool in Nueva Gorgona

KristoferRating, 5 stars1 month ago
Vielka is a wonderful host. She is very responsive and very helpful and accommodating. The home is beautiful and perfect for large groups. I would return again.
Superhost
Cabin in Calobre
4.83 out of 5 average rating, 18 reviews

La Yeguada - Forest Point Cabin

StefanieRating, 5 stars1 month ago
Flexible check-in, variety of kitchen utilities and so on that made the stay very pleasant, everything clean and organized.
Guest favourite
Villa in El Chirú
4.88 out of 5 average rating, 41 reviews

Beach house for families with a pool.

CarlosRating, 5 stars2 weeks ago
Great outdoor space to relax and enjoy with the family, bbq area was great and plenty of space to chill. Pool was very good and clean! Couple of minutes walk to the beach which was great!
Guest favourite
Villa in Paso Ancho
4.95 out of 5 average rating, 84 reviews

Charming & Enjoyable Cabin surrounded by trees

VivianRating, 5 stars3 weeks ago
A hidden gem in the middle of nature! The cabin was spotless, very comfortable and exactly as shown in the pictures. Our stay in this cabin surrounded by trees was excellent. The place is even more beautiful in person, with spectacular views, clean and cozy spaces, and an atmosphere of total tranquility. Perfect for disconnecting and enjoying with family or friends. The host was very attentive and made sure we made sure we had everything we needed. We would definitely come back! Highly recommended for those looking for peace, fresh air and natural beauty.
Top guest favourite
Villa in Punta Chame
4.97 out of 5 average rating, 121 reviews

Beach House with Pool/Gazebo in Punta Chame!

SauliRating, 5 stars6 days ago
Hi, we loved everything! The location, the place is very nice and quiet. The house is very beautiful and very cozy, everything was in excellent condition, very clean. It has everything you need to feel comfortable, like at home, we love every detail, we did not expect to find products for personal hygiene, and others, it seemed like a beautiful detail . Communication with the hostess was excellent. We would definitely repeat it again, thank you very much❤️
Guest favourite
Home in Playa Coronado
4.84 out of 5 average rating, 19 reviews

Spacious home in Coronado Golf

KeysiRating, 5 stars2 months ago
Beautiful accommodation, the house was super spacious, quiet, the rooms were beautiful each room had its own bathroom. The clean, beautiful garden overlooking the golf course, the terrace in front of the pool was ideal for breakfast and dinner together! I definitely look forward to coming back and recommend it 100%. The host Alexandra was always attentive, responsive and very friendly. Thank you for everything

Mansion rentals with a pool

Top guest favourite
Home in Panama City
5 out of 5 average rating, 30 reviews

Mountain Retreat

NelsonRating, 5 stars2 weeks ago
Recommend this place.
Guest favourite
Villa in Rio Hato
5 out of 5 average rating, 28 reviews

Villa Agueda Decameron, golf club and swimming pool

JeremyRating, 5 stars3 months ago
What a place, one of the better Air B &B’s in Panama, have everything you require, nice pool, cold jacuzzi that works, very amazing stay Annelise, thanks for everything.
Superhost
Villa in Santa Catalina
4.84 out of 5 average rating, 58 reviews

Infinity Pool Boutique Villa on The Point Break

Lisa & BrettRating, 5 stars1 week ago
Lovely house! Great layout. Note that the downstairs rooms by the pool are outside of the main house. Pool was clean. Beds were comfortable. Kitchen had all necessities. AC worked well. Power goes off about once a day anywhere from 10-90 minutes (usually closer to 10). We did need a car to drive the 10 minutes into town as well as to Playa Estero (with 3 slow moving small kids + surf boards). Pietro is extremely accommodating! I would definitely stay here again with family or friends.
Superhost
Cabin in Chame District
4.7 out of 5 average rating, 30 reviews

A private place for events and parties

ChristianRating, 5 stars4 months ago
The Place is perfect to enjoy with family and friends, it's a very peaceful and beautiful place. Mr. Ahmed is a great person with a good communication and a friendly host. Really worth it!
Guest favourite
Home in Panama City
4.95 out of 5 average rating, 38 reviews

Nice duplex house with a swimming pool.

AravinthRating, 5 stars5 days ago
Absolutely loved our stay at Gerardo's place. Not just the place but also the host makes the airbnb rental pleasant and memorable. Gerardo and his house did just that. Gerardo was there to answer all of our questions and address our concerns from the moment we booked the place. He greeted us when we arrived and showed the house around to ensure we felt comfortable. He also provided suggestions for restaurants and excursions. He even helped us find the cell phone left in an Uber!!! The house is huge but was kept clean inside and out - true to the photos on airbnb. It is also conveniently located in a quiet and safe neighborhood. The swimming pool and surrounding areas were cleaned everyday. Clean towels were provide everyday by the pool. The BBQ machine by the pool made the whole thing even better. Overall, this is the place to stay if you are visiting Panama City.
Top guest favourite
Villa in Boca Chica
5 out of 5 average rating, 13 reviews

On the Beach Villa in Boca Chica!

CoreyRating, 5 stars1 week ago
This place is amazing! Super special location with a beach to surf right outside your back door. Gated community provided great security, we left our car and doors unlocked the whole time with zero concern. Lance and Monty are plugged into the local community and have great recommendations for anything you'd like to do. If you like remote, beautiful locations without tourists buzzing all over then this is the right place.
Superhost
Home in Panamá
4.84 out of 5 average rating, 25 reviews

Spectacular Beach Cabin "Tiny House" San Carlos

victorRating, 5 stars1 month ago
Comfortable and quiet place to spend as a family. Very good communication with Roberto. 10/10
Superhost
Villa in San Carlos
4.71 out of 5 average rating, 34 reviews

Casa Helechos, in a beach community with a swimming pool

AngelaRating, 5 stars6 days ago
We loved the house, it is central, close to the super It looks much Better in person than in the photos, super spacious and comfortable, it has all the necessary utensils, the beach is close by. The host's attention is very rewarding, attentive and very friendly.

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