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Mansion vacation rentals in Panama

Find and book unique mansions on Airbnb

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Popular amenities for Panama mansion rentals

Luxury mansion rentals

Guest favourite
Villa in Las Lajas
4.82 out of 5 average rating, 33 reviews

Casa de Playa Donde Emy

TylerRating, 5 stars2 months ago
Great place we want to go back already.
Superhost
Home in La Ermita
4.83 out of 5 average rating, 12 reviews

2 beachfront houses, spectacular private beach.

AlexRating, 5 stars3 months ago
buena atencion, casa super equipada que fue lo que mas nos gusto , acceso hermoso de playa y rio super cerca , fue maravillosa la estadia ... sigan asi.
Guest favourite
Cottage in Panama City
5 out of 5 average rating, 18 reviews

Hacienda La Perezosa en Cerro Azul

KarinaRating, 5 stars2 months ago
Llevábamos muy altas expectativas del lugar y no nos defraudó. Desde nuestra llegada nos sentimos bienvenidos. El lugar te ofrece el servicio de una ama de llaves que te ayuda durante tu estadía, nos recibió como si estuviéramos llegando a donde un familiar, nos asistía en la cocina. Preparaba el desayuno, y cualquier otro apoyo que requiriéramos en la cocina en otros momentos. El lugar es cómodo para 10 personas, espacioso, tiene un hermoso lago que solo estar ahí vale todo la pena, puedes andar en kayaks que están incluidos, caminar por la propiedad, jugar juegos de mesa o hacer actividades fuera como jugar a la pelota. Pudimos llevar a los perritos que estuvieron felices. En verdad queremos volver. Importante llevar sus comidas porque no hay restaurantes cerca. No se arrepentirán de ir a Hacienda la Perezosa y van a querer volver. Felicidades por este hermoso lugar a solo 1 hora de la ciudad.
Superhost
Villa in Rio Hato
4.86 out of 5 average rating, 44 reviews

La Casa de las Uvas un oasis con vistas al mar

LoriRating, 5 stars1 month ago
Wonderful stay. The pool, beautiful trees and well thought out outdoor seating was the perfect setting for our large family to vacation. Easy walk to the beach and restaurants. House had everything we needed. Mónica was very responsive to a very small issue we had and it was quickly remedied. Absolutely recommend.
Superhost
Home in Coronado
4.76 out of 5 average rating, 25 reviews

ENCANTADORA CASA FRENTE ALMAR CON PISCINA-CORONADO

MathieuRating, 5 stars1 month ago
I really loved the Hamacas casa What a beautiful place You can’t go wrong being right on the beach Lots of restaurants near by Super safe to walk around Coronado Marcella was super helpful and answered Us every time we had a question The house was great mind you we didn’t really stay in the house other than going to bed Daniel the grounds keeper was super nice and helpful All and all I wouldn’t definitely rent this place again hopefully in a bear future
Guest favourite
Apartment in Panama City
4.96 out of 5 average rating, 25 reviews

22M Spectacular Penthouse New Design Oceanview

ShawnRating, 5 stars5 months ago
I had an absolutely wonderful stay at Melissa’s place! The space was clean, beautifully maintained, and thoughtfully designed for comfort. Melissa was an exceptional host—very responsive, kind, and accommodating throughout my visit. The location was perfect, with easy access to local attractions and everything I needed nearby. I truly felt at home and appreciated the attention to detail that made my stay so relaxing. I highly recommend this Airbnb and would love to stay here again in the future!
Guest favourite
Villa in Isla Colon
4.89 out of 5 average rating, 9 reviews

Casa Caracola. Luxury villa. 200 mts from beach

GiyoraRating, 5 stars2 months ago
Our stay at casa Caracola was simply exceptional. It is a spacious, luxurious and perfect for two families. From the moment we arrived, we felt so comfortable that we hardly needed to go anywhere. We spent our days enjoying the beautiful garden and swimming pool, where we had the privilege of seeing toucans, monkeys, and a variety of wild birds. Waking up each morning to the sound of birds singing was an incredible experience. The host, Ricardo, was outstanding. He helped us arrange everything, from private chefs who prepared spectacular meals at the house to booking tours and surf and diving lessons. His attention to detail and willingness to assist made our stay even more special. We also want to highlight Nely, who took care of keeping the house spotless throughout our stay. It was a pleasure to have her help in maintaining everything clean and organized. We will definitely be back. A perfect place for an unforgettable getaway! Thanks Gigi
Guest favourite
Home in Bocas del Toro
4.92 out of 5 average rating, 25 reviews

Architectural Waterfront Home- "Casa Comunal"

FrankRating, 5 stars3 months ago
Fantastische plek, de zee is je achtertuin. Apen, volgels, eekhoorns en op de golven voorbij komende surfers. Geweldig huis, minimalistisch maar heel leuk mit diverse hangplekken. Hou er wel rekening mee dat het warm kan zijn in het huis en dat er insecten makkelijk binnen kunnen komen....maar daar staat iets geweldigs tegenover.

Pet-friendly mansion rentals

Superhost
Place to stay in Portobelo
4.9 out of 5 average rating, 21 reviews

Villa Frente al Mar

AdrianaRating, 5 stars2 months ago
This place is perfect to enjoy a relaxing het away, having the beautiful ocean view and tropical breeze right outside of the house it is priceless! The pool and Jacuzzi are well maiy and make a great complement of the whole experience! The host thought about every detail to make the guests very welcome, by providing essentials for personal cleaning products, kitchen extra essentials and outdoors supplies. We really enjoyed the stay.!
Superhost
Cottage in Panamá Oeste
4.83 out of 5 average rating, 12 reviews

Iwanna Green, Casa de Campo con Piscina

MonicaRating, 5 stars5 months ago
Una casa totalmente ecológica con actividades para todo la familia, una piscina rodeada de naturaleza y una temática que da ganas de sacar tu niño interior y pasarla bien con amigos y familia mientras estas rodeado de un clima fresco en la montaña de campana. Fácil acceso, diversidad e arte neón en cada área de la casa, múltiples utensilios de cocina y electrodomésticos. .
Top guest favourite
Home in Nueva Gorgona
5 out of 5 average rating, 21 reviews

Comfortable beach house with pool in Nueva Gorgona

KristoferRating, 5 stars1 month ago
Vielka is a wonderful host. She is very responsive and very helpful and accommodating. The home is beautiful and perfect for large groups. I would return again.
Superhost
Cabin in Calobre
4.83 out of 5 average rating, 18 reviews

La Yeguada - Forest Point Cabin

StefanieRating, 5 stars1 month ago
Check in flexible, variedad de utilidades de cocina y demás que hicieron la estadía muy agradable, todo limpio y organizado.
Guest favourite
Villa in El Chirú
4.88 out of 5 average rating, 41 reviews

Casa de Playa para Familias con Piscina.

CarlosRating, 5 stars2 weeks ago
Great outdoor space to relax and enjoy with the family, bbq area was great and plenty of space to chill. Pool was very good and clean! Couple of minutes walk to the beach which was great!
Guest favourite
Villa in Paso Ancho
4.95 out of 5 average rating, 84 reviews

Charming & Enjoyable Cabin surrounded by trees

VivianRating, 5 stars3 weeks ago
¡Una joya escondida en medio de la naturaleza! La cabaña estaba impecable, muy cómoda y exactamente como se muestra en las fotos. Nuestra estadía en esta cabaña rodeada de árboles fue excelente. El lugar es aún más hermoso en persona, con vistas espectaculares, espacios limpios y acogedores, y un ambiente de tranquilidad total. Perfecto para desconectarse y disfrutar con familia o amigos. El anfitrión fue muy atento y se aseguró de que tuviéramos todo lo necesario. ¡Definitivamente volveríamos! Muy recomendado para quienes buscan paz, aire fresco y belleza natural.
Top guest favourite
Villa in Punta Chame
4.97 out of 5 average rating, 121 reviews

Beach House with Pool/Gazebo in Punta Chame!

SauliRating, 5 stars6 days ago
Hola, nos encantó todo! la ubicación, el lugar es muy lindo y tranquilo. La casa es muy hermosa y muy acogedora, todo estaba en excelente condiciones, muy limpio. Cuenta con todo lo necesario para sentirse cómodos, como en casa, amamos cada detalle, no esperábamos encontrar productos para el aseo personal, y otros, nos pareció un hermoso detalle . La comunicación con la anfitriona fue excelente. Definitivamente volveríamos a repetirlo, muchas gracias❤️
Guest favourite
Home in Playa Coronado
4.84 out of 5 average rating, 19 reviews

Spacious home in Coronado Golf

KeysiRating, 5 stars2 months ago
Hermoso alojamiento, la casa era súper espaciosa, tranquila, las habitaciones estaban hermosas cada habitación tenía su propio baño. El jardín limpio, hermoso con vista al campo de Golf, la terraza frente a la piscina fue ideal para desayunar y cenar juntos! Sin duda espero regresar y lo recomiendo 100%. La anfitriona Alexandra siempre atenta, respondía rápido y muy amable. Gracias por todo !

Mansion rentals with a pool

Top guest favourite
Home in Panama City
5 out of 5 average rating, 30 reviews

Mountain Retreat

Juan DiegoRating, 5 stars2 days ago
Hermosa y acogedora casa rodeada de naturaleza. La casa cuenta con todas las comodidades para pasar un buen rato en familia.
Guest favourite
Villa in Rio Hato
5 out of 5 average rating, 28 reviews

Villa Agueda Decameron, club de golf y piscina

AlexanderRating, 5 stars4 months ago
¡Una experiencia maravillosa! Nos hospedamos en la casa de Anneliese durante nuestras vacaciones, y no podemos estar más agradecidos. Ella fue increíblemente atenta y siempre estuvo disponible para cualquier duda o necesidad que tuviéramos. La casa es simplemente maravillosa: limpia, cómoda y equipada con todo lo necesario para que nuestra estadía fuera perfecta. Además, su ubicación era ideal, lo que hizo que nuestras vacaciones fueran aún más agradables. Recomendamos este lugar al 100% y, sin duda, volveríamos en el futuro. ¡Gracias, Anneliese, por hacer de nuestras vacaciones una experiencia inolvidable!
Superhost
Villa in Santa Catalina
4.84 out of 5 average rating, 58 reviews

Infinity Pool Boutique Villa on The Point Break

Lisa & BrettRating, 5 stars1 week ago
Lovely house! Great layout. Note that the downstairs rooms by the pool are outside of the main house. Pool was clean. Beds were comfortable. Kitchen had all necessities. AC worked well. Power goes off about once a day anywhere from 10-90 minutes (usually closer to 10). We did need a car to drive the 10 minutes into town as well as to Playa Estero (with 3 slow moving small kids + surf boards). Pietro is extremely accommodating! I would definitely stay here again with family or friends.
Superhost
Cabin in Chame District
4.7 out of 5 average rating, 30 reviews

Un lugar privado,para eventos y fiestas

ChristianRating, 5 stars4 months ago
The Place is perfect to enjoy with family and friends, it's a very peaceful and beautiful place. Mr. Ahmed is a great person with a good communication and a friendly host. Really worth it!
Guest favourite
Home in Panama City
4.95 out of 5 average rating, 38 reviews

Agradable Casa Duplex con piscina.

AravinthRating, 5 stars5 days ago
Absolutely loved our stay at Gerardo's place. Not just the place but also the host makes the airbnb rental pleasant and memorable. Gerardo and his house did just that. Gerardo was there to answer all of our questions and address our concerns from the moment we booked the place. He greeted us when we arrived and showed the house around to ensure we felt comfortable. He also provided suggestions for restaurants and excursions. He even helped us find the cell phone left in an Uber!!! The house is huge but was kept clean inside and out - true to the photos on airbnb. It is also conveniently located in a quiet and safe neighborhood. The swimming pool and surrounding areas were cleaned everyday. Clean towels were provide everyday by the pool. The BBQ machine by the pool made the whole thing even better. Overall, this is the place to stay if you are visiting Panama City.
Top guest favourite
Villa in Boca Chica
5 out of 5 average rating, 13 reviews

On the Beach Villa in Boca Chica!

CoreyRating, 5 stars1 week ago
This place is amazing! Super special location with a beach to surf right outside your back door. Gated community provided great security, we left our car and doors unlocked the whole time with zero concern. Lance and Monty are plugged into the local community and have great recommendations for anything you'd like to do. If you like remote, beautiful locations without tourists buzzing all over then this is the right place.
Superhost
Home in Panamá
4.84 out of 5 average rating, 25 reviews

Espectacular Cabaña Playa " Tiny House" San Carlos

victorRating, 5 stars1 month ago
Lugar comodo y tranquilo para pasarla en familia. Muy buena comunicacion con Roberto. 10/10
Superhost
Villa in San Carlos
4.71 out of 5 average rating, 34 reviews

Casa Helechos, en comunidad de Playa con piscina

AngelaRating, 5 stars6 days ago
Nos encantó la casa, es céntrica, cerca de los súper Se ve mucho Mejor en persona que en las fotos, súper espaciosa y cómoda, cuenta con todos los utensilios necesarios, la playa está cerca. La atención del anfitrión muy gratificante, atento y muy amable.

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